BPC-157

BPC-157

Body Protection Compound‑157

Also referenced as: PL14736 · Body Protection Compound 157 · Gastric Pentadecapeptide BPC 157 · Pentadecapeptide BPC 157

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Certificate Of Analysis

TestResultStatus
Identity & Purity (Avg, HPLC + MS)99.72%PASS
Net Peptide Weight (Avg)10.6 mgPASS
Heavy Metals (ICP-MS)<0.010 ppb/vialPASS
Endotoxins (LAL Assay)<0.05 EU/mLPASS
Sterility (DNA Microarray)Not Included In This COAN/A

Made in cGMP- and ISO-certified facilities our supply chain has vetted in person, then independently multi-lab tested by Virtus with a final Certificate of Analysis from ILS Laboratories. We pay more to source this way because we hold the highest standard for the product and for you.

Batch 961235 · Tested Apr 29, 2026 · Motzz Laboratory, Inc.

View the full Certificate of Analysis →

PubMed Research

Curated research on BPC-157

  • Seiwerth S (2021). Stable Gastric Pentadecapeptide BPC 157 and Wound Healing Front Pharmacol.

    PMID: 34267654
  • Sikiric P (2020). Stable Gastric Pentadecapeptide BPC 157, Robert's Stomach Cytoprotection/Adaptive Cytoprotection/Organoprotection, and Selye's Stress Coping Response Gut Liver.

    PMID: 31158953
  • Gwyer D (2019). Gastric pentadecapeptide body protection compound BPC 157 and its role in accelerating musculoskeletal soft tissue healing Cell Tissue Res.

    PMID: 30915550
  • Sikiric P (2022). Stable Gastric Pentadecapeptide BPC 157 as Useful Cytoprotective Peptide Therapy Biomedicines.

    PMID: 36009512

About BPC-157

A synthetic pentadecapeptide composed of 15 amino acids investigated extensively in controlled laboratory environments. BPC-157 is among the most studied research peptides in preclinical literature, with published data examining its role in cellular signaling, nitric oxide pathway modulation, cytokine expression, and extracellular matrix interactions.

Research in controlled laboratory models has examined BPC-157 activity across multiple cellular systems including fibroblast signaling, angiogenesis pathway modulation, and inflammatory cytokine regulation at the cellular level. Its stability profile and receptor interaction mechanisms make it a widely referenced compound in tissue and recovery research literature.

Also Referenced As

PL14736 · Body Protection Compound 157 · Gastric Pentadecapeptide BPC 157 · Pentadecapeptide BPC 157

Specifications

Scientific Name
Body Protection Compound-157
CAS Number
137525-51-0
Molecular Formula
C₆₂H₉₈N₁₆O₂₂
Molecular Weight
1,419.54 g/mol
Physical Form
Lyophilized powder
Purity
99%+
Batch Number
23747
Storage
−20°C, protected from light

Storage & Handling

Lyophilized peptides remain stable for 12–24 months when stored properly. Follow standard laboratory protocols for handling.

Storage

Store lyophilized peptide at −20°C in a standard laboratory freezer, protected from light, moisture, and heat. Avoid repeated freeze-thaw cycles.

Shelf Life

Lyophilized form remains stable for 12–24 months at −20°C in the original sealed vial. Always reference the batch-specific COA for verified shelf-life data.

Mechanism & Research Background

BPC-157 (Body Protection Compound 157) is a synthetic 15-amino acid peptide whose sequence corresponds to a fragment of a larger protein originally isolated from human gastric juice. Identified in early research literature under the developmental code PL14736, BPC-157 has accumulated one of the most extensive preclinical research corpora of any synthetic peptide on PubMed, with over 100 published papers spanning more than two decades. Its 15-residue sequence (Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val) gives the peptide notable stability in research model systems, including reported resistance to proteolytic degradation in gastric-acid-mimicking environments.

In pathway research, BPC-157 has been examined across multiple cellular systems, most prominently angiogenesis pathway markers, nitric oxide signaling, cytokine expression, and fibroblast biology in preclinical literature. Foundational mechanistic work by Sikiric, Seiwerth, and colleagues has characterized BPC-157 activity in laboratory models examining endothelial cell behavior, growth factor expression, and inflammatory cytokine modulation (Sikiric et al., Gut Liver, 2020; Seiwerth et al., Front Pharmacol, 2021). Distinct from peptides that act through a single canonical receptor, BPC-157's research literature describes a multi-pathway interaction profile under active investigation.

Studied effects in research models include modulation of nitric oxide synthase expression, vascular endothelial growth factor pathway markers, and cellular markers associated with extracellular matrix turnover and tissue repair (Gwyer et al., Cell Tissue Res, 2019). BPC-157 remains one of the most heavily referenced compounds in tissue and recovery research literature; products supplied by Virtus Peptides are intended exclusively for in-vitro laboratory research and are not for human or animal use.

Frequently Researched Questions

What is BPC-157?

BPC-157 (Body Protection Compound 157) is a synthetic 15-amino acid peptide whose sequence corresponds to a fragment of a protein originally identified in human gastric juice. It is referenced in research literature under the developmental code PL14736 and has accumulated extensive peer-reviewed preclinical research on PubMed. Virtus Peptides supplies BPC-157 as a lyophilized powder strictly for in-vitro laboratory research.

What is the amino acid sequence of BPC-157?

BPC-157 is a 15-amino acid pentadecapeptide with the sequence Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val. The "157" in the name refers to the residue position within the larger Body Protection Compound source protein from which the fragment was identified.

What is BPC-157's molecular weight?

BPC-157 has a molecular weight of approximately 1,419.54 g/mol with the molecular formula C₆₂H₉₈N₁₆O₂₂.

What does PL14736 mean?

PL14736 is the developmental code under which BPC-157 was investigated in early preclinical research literature. The two terms refer to the same peptide and both appear in PubMed search results.

What testing does Virtus run on BPC-157?

Every batch of Virtus BPC-157 is independently tested by ILS Laboratories (ISO/IEC 17025 accredited) across the full QC panel: identity and purity by HPLC and LC-MS, net peptide weight, heavy metals by ICP-MS, bacterial endotoxin, and a rapid sterility screen. Purity and net peptide weight are averaged across three vials per batch to confirm conformity. The full Certificate of Analysis is published in our COA database before any vial ships.

What is the recommended storage temperature for BPC-157?

Lyophilized BPC-157 should be stored at −20°C, protected from light, in the original sealed vial. Repeated freeze-thaw cycles should be avoided. When stored correctly, lyophilized peptides typically maintain stability for 12–24 months.

Where can I find published research on BPC-157?

BPC-157 is one of the most heavily indexed peptides on PubMed with over 100 peer-reviewed papers. Search "BPC-157", "PL14736", or "gastric pentadecapeptide". Foundational mechanistic work by Sikiric, Seiwerth, and colleagues spans more than two decades of preclinical research literature.